I try to use it every morning and night. After washing my face, I follow up with my full skincare routine and then as a last step, use the Medicube Collagen Jelly Cream.To be totally clear, you do not have to use their creams or serums to use the Booster. I just recently returned to using the cream because it’s thick and helps the booster slide more easily around my face LTKGiftGuide LTKBeauty