L-Methylfolate and 5-MTHR help you absorb folate if you have a deficiency or a gene mutation like MTHFR gene mutation found in many people who have hypermobile ehlers Danlos syndrome. I’ve seen benefits of taking this in just a short period of time in improved cognitive function. heds folate folicacid mthfr Methlyfolate activefolate LTKHome LTKOver40