Over 50 and not taking estrogen? These supplements matter even more. As estrogen declines in midlife, it affects everything from brain health to bones, skin, and even bladder function. As a pharmacist, these are three supplements I often suggest women consider supporting. ⭐️ Omega-3 Fatty Acids Estrogen plays a protective role in both brain and cardiovascular health. Omega-3s support these same systems while also helping reduce inflammation linked to chronic disease. Many women also notice benefits for mood, perceived stress, and skin hydration, giving that healthy midlife glow. ⭐️ Vitamin D Vitamin D is essential for bone strength and cellular health, which become even more important after estrogen declines. Low vitamin D levels are also common in women with pelvic floor weakness and overactive bladder symptoms, making it a key nutrient to optimize in midlife. ⭐️ Collagen Collagen production drops with age and lower estrogen levels. Supplementing collagen may help support joint comfort, bone health, and the appearance of hair and skin—all areas many women notice changing in their 50s and beyond. Biosil helps your body make its own collagen and my favorite grass fed beef protein is high in collagen too! These three can be powerful foundational supports for women navigating midlife without estrogen therapy. This content is educational only. Always check with your healthcare professional before starting new supplements. Check out my favorites here! LTKOver40 LTKselfcare